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Presented by the Johns Hopkins University School of Medicine.

Supported by an educational grant from Lilly USA, LLC.

CASE 1: Older Man with Decreased Memory and Additional Symptoms

Ronald S. Swerdloff, MD, and Prasanth Surampudi, MD

OVERVIEW

Male hypogonadism is a condition that is severely underrecognized and underdiagnosed. The diagnosis of hypogonadism in men is based on a combination of clinical signs and symptoms and laboratory tests. The most commonly noted symptoms include rather vague complaints such as lack of energy, loss of motivation, cantankerous mood, inability to concentrate, and sexual symptoms such as loss of desire, sexual dysfunction, erectile difficulties, impotence, and decreased ejaculate volume. In addition, the relationship between hypogonadism and other comorbidities, such as diabetes, obesity, hypertension, and Alzheimer disease, is a very important and dynamic topic for which new data are continuously emerging. Proper treatment may prevent many of the comorbidities and ameliorate health. Using an interactive case-based format, this educational activity discusses the prevalence of male hypogonadism, comorbidities associated with the disease, and the role of testosterone replacement therapy, to help primary care physicians improve the diagnosis, management, and treatment of this condition, ultimately improving their patients’ quality of life.

GOAL

To provide primary care physicians with up-to-date information on the diagnosis, management, and treatment of male hypogonadism.

TARGET AUDIENCE

This activity is designed for primary care physicians. No prerequisites required.

LEARNING OBJECTIVES

After completing this activity, the participant should demonstrate the ablity to:

  • STATE the prevalence of male hypogonadism in the general male population and in those with associated comorbid conditions.
  • IDENTIFY 3 health-related risk factors and/or comorbid conditions associated with male hypogonadism.
  • ANALYZE the role of testosterone replacement therapy in improving the health and quality of life of men with hypogonadism.

The Johns Hopkins University School of Medicine takes responsibility for the content, quality, and scientific integrity of this CME activity.

ACCREDITATION STATEMENT

The Johns Hopkins University School of Medicine is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians.

CREDIT DESIGNATION STATEMENT

The Johns Hopkins University School of Medicine designates this enduring material for a maximum of 0.5 AMA PRA Category 1 Credit(s)™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

After reviewing this online activity, participants may receive credit by completing the CME test, evaluation, and receiving a score of 75% or higher.

The estimated time to complete this activity: 30 minutes.

Release date: March 1, 2011. Expiration date: March 1, 2013.

FULL DISCLOSURE POLICY AFFECTING CME ACTIVITIES

As a provider accredited by the Accreditation Council for Continuing Medical Education (ACCME), it is the policy of the Johns Hopkins University School of Medicine to require the disclosure of the existence of any relevant financial interest or any other relationship a faculty member or a provider has with the manufacturer(s) of any commercial product(s) discussed in an educational presentation. The Planning Committee and Participating Faculty reported the following:

Adrian Dobs, MD, MHS (Chair)
Professor of Medicine and Oncology
Johns Hopkins University School of Medicine
Division of Endocrinology and Metabolism
Baltimore, Maryland

Ronald S. Swerdloff, MD
Professor and Chief Division of Endocrinology
Harbor-UCLA Medical Center
David Geffen School of Medicine at UCLA
Los Angeles Biomedical Research Institute
Torrance, California

Prasanth Surampudi, MD
Senior Research Fellow
Division of Endocrinology
Harbor-UCLA Medical Center
David Geffen School of Medicine at UCLA
Los Angeles Biomedical Research Institute
Torrance, California

Participating Faculty Disclosures
Dr Swerdloff reports receiving grants from Abbott (Solvay Pharmaceuticals, Inc), Clarus Corporation, Lilly, USA, LLC, and the National Institutes of Health; and serving as a consultant for Abbott (Solvay Pharmaceuticals, Inc), Clarus Corporation, Endo Pharmaceuticals, Lilly, USA, LLC, the National Institutes of Health, and Repros Therapeutics.

No other speakers have indicated that they have any financial interests or relationships with a commercial entity whose products or services are relevant to the content of their presentation(s).

Planner Disclosures
Dr Dobs reports serving as a principal investigator for grants from Lilly, USA, LLC, the National Institutes of Health, and Takeda Pharmaceutical Company Limited; and serving as a consultant for Abbott, Auxilium, and Lilly, USA, LLC.

Dr Swerdloff reports receiving grants from Abbott (Solvay Pharmaceuticals, Inc), Clarus Corporation, Lilly, USA, LLC, and the National Institutes of Health; and serving as a consultant for Abbott (Solvay Pharmaceuticals, Inc), Clarus Corporation, Endo Pharmaceuticals, Lilly, USA, LLC, the National Institutes of Health, and Repros Therapeutics.

No other planners have indicated that they have any financial interests or relationships with a commercial entity.

Grants to investigators at The Johns Hopkins University are negotiated and administered by the institution that receives the grants, typically through the Office of Research Administration. Individual investigators who participate in the sponsored project(s) are not directly compensated by the sponsor, but may receive salary or other support from the institution to support their effort on the project(s).

OFF-LABEL PRODUCT DISCUSSION

No faculty member has indicated that their presentation will include information on off-label products.

DISCLAIMER

The opinions and recommendations expressed by faculty and other experts whose input is included in this activity are their own. This activity is produced for educational purposes only. Use of Johns Hopkins University School of Medicine name implies review of educational format, design, and approach. Please review the complete prescribing information of specific drugs or combinations of drugs, including indications, contraindications, warnings, and adverse effects before administering pharmacologic therapy to patients.

INTERNET CME POLICY

The Office of Continuing Medical Education (CME) at the Johns Hopkins University School of Medicine is committed to protect the privacy of its members and customers. Johns Hopkins University SOM CME maintains its Internet site as an information resource and service for physicians, other health professionals, and the public. Continuing Medical Education at the Johns Hopkins University School of Medicine will keep your personal and credit information confidential when you participate in a CME Internet based activity. Your information will never be given to anyone outside of the Johns Hopkins University School of Medicine’s CME activity. CME collects only the information necessary to provide you with the services that you request.

ACTIVITY

Instructions
The following are interactive educational case modules designed to help you gauge your basic knowledge of the topic and direct you to areas you may need to focus on. They consists of 3 sections: a pre-test, an interactive case activity, and a CME post-test with an evaluation. All 3 sections must be completed to receive CME credit. A certificate of participation will be available online immediately following successful completion of the module.

 
procced to pretest




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