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Cardiovascular diseases are the most common cause of mortality and morbidity accounting for more than 40% of total mortality in Western countries. Most of this is due to acute coronary syndrome (ACS), including ST and non-ST elevation myocardial infarction. An optimal pharmacologic approach in these patients is of major importance with a particular emphasis on the antiplatelet regimen, which remains the cornerstone of the initial ACS treatment at hospital admission and during percutaneous coronary interventions. Although management guidelines from the American College of Cardiology and the American Heart Association have been published and widely accepted, barriers to the optimal treatment of patients with ACS still exist and opportunities to provide guideline-recommended care are missed. The following initiative includes 3 educational activities. Using case studies and interactive formats, these activities discuss the efficacy and safety of various antiplatelet therapies, provide methods for selecting the proper therapy for specific patients, and examine the utility of different genetic and laboratory tests in order to improve patient management and outcomes.


To provide cardiologists and internists with up-to-date information on the treatment and management of ACS.


This activity is designed for cardiologists and internists. No prerequisites required.


After completing this activity, the participant will demonstrate the ability to:

  • COMPARE the efficacy and safety of new and emerging antiplatelet therapies.
  • DISCUSS selection of appropriate antiplatelet therapy for individuals, special populations, and patients on concomitant medications.
  • SUMMARIZE the utility of genetic testing, the laboratory tests available, and the most effective treatment plans for patients with ACS.
  • APPLY the most recent randomized clinical trial data relating antiplatelet therapy to the management of patients with ACS.

The Johns Hopkins University School of Medicine takes responsibility for the content, quality, and scientific integrity of this CME activity.

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